The Use of Nanotechnology in Diagnosing Brain Disease

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The Use of Nanotechnology in Diagnosing Brain Disease

Nanotechnology was proved to be useful in diagnosing brain problems / Photo by: Kateryna Kon via Shutterstock


One of the primary parts of the human’s body is the brain. It acts like a control center that dictates and manages the body’s overall control. However, circumstances such as accidents and diseases could happen in an individual’s life and change the way they live their life. Once that the brain become affected by accident or damaged by a disease, it could have affected a lot of things including the memory, sensation, and even the personality and behavior of the person. Moreover, inflammation in the brain can lead to problems such as vision loss, weakness, and paralysis. A patient who suffered from stroke could lose some brain cells which could affect their ability to think clearly.

MedlinePlus explained that the symptoms of a brain disease are different and it depends on the specific problem. Sometimes, the damage may be too severe and its damage will be permanent, while there are some cases that brain damage can be healed through treatment such as surgery, medicines, or physical therapy. Furthermore, with the advancements made on the medical science, experts found a new way on how they could use nanotechnology to help the health practitioners in diagnostics and healing different kinds of brain diseases. In a website called News Medical, they reported that in a recent transnational research project funded by the EU Joint Program on Neurodegenerative Disease Research (JPND), researchers are now trying to address the question on how they will prevent the death of neurons which could lead to dementia and other brain diseases.

Likewise, Mainz scientists are working on the nanocapsules which are believed to overcome the barrier, but scientists noted that it should be taken cared of for a long period of time in order for the nanocapsules to work on the blood more efficiently and more accurately. It will increase the probability of interaction with the target cells which are located on the affected area of the brain. In a website called Eurekalert, they explained that it is important that the design of the nanocapsule is appropriate so that it will not be directly excreted by the kidney or liver. Special address labels which consist of proteins must be placed on the capsule surface in order to be absorbed and recognized by the target cells. “If the transport through the blood-brain barrier with the nanocarriers works, we hope we can simply exchange the dye for a suitable drug,” says Dr. Svenja Morsbach, the group leader in the department of Prof. Katharina Landfester at the MPI-P. She also added that her teams are still filling the nanoscale capsule with dye.


Modern scientists are now working on the development of nanocapsules / Photo by: ranz12 via Shuttersock


Nanotechnology against brain diseases

Having a brain disease could be very hard for the patient and his/her family. It will definitely change their lives forever once the disease struck them. Thankfully, as technology thrives, the healthcare services also thrive and are finding their own way into helping their patients to overcome their disease by making advanced technology that could help them in providing an accurate diagnosis in different brain diseases. In an article published by Medical Xpress, they mentioned that a project called EXIT (Exosomes Isolation Tool) is part of a multidisciplinary team that will develop an analytical tool which is designed to examine exosomes in the samples taken from patients who suffer from Alzheimer’s disease. Exosomes are natural nanoscopic particles which are released by most cell types. These particles are not easy to isolate and experts and scientists believe that nanotechnology could help them in this particular process.

Nanoparticles could help create more effective medical treatments. The aim is to improve areas ranging from drug delivery to the detection of diseases and experts believe the nanoparticles will be beneficial in the possibility of developing targeted therapies.



Understanding dementia

Dementia is defined as the decline in the mental ability which is severe enough to interfere with the life of the patient. Alzheimer’s disease accounts for 60 to 80 percent of the cases of dementia. Dementia is often incorrectly referred to as “senility” or “senile dementia”, which reflects the formerly widespread but incorrect belief that serious mental decline is part of aging. People who suffer from dementia can become apathetic or uninterested in their usual activities, or may have problems controlling their situations. They may also find social situations to become more challenging and lose interest in socializing.



Although there is no current cure available to fight dementia, there are ways on how patients can slow it down and maintain their mental function. An accurate diagnosis could help people with dementia to get the right treatment and support and help those who are close to them to be prepared and plan for their future. The symptoms of dementia tend to worsen with time. In the much later stages of dementia, people will be able to do far less for themselves and may lose much of their ability to communicate.



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